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Keratin 9

From Wikipedia, the free encyclopedia

KRT9
Identifiers
AliasesKRT9, CK-9, EPPK, K9, keratin 9
External IDsOMIM: 607606; MGI: 96696; HomoloGene: 133554; GeneCards: KRT9; OMA:KRT9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000226

NM_201255

RefSeq (protein)

NP_000217

NP_957707

Location (UCSC)Chr 17: 41.57 – 41.57 MbChr 11: 100.08 – 100.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin 9 is a protein that in humans is encoded by the KRT9 gene.[5][6]

Keratin 9 is a type I cytokeratin. It is found only in the terminally differentiated epidermis of palms and soles. Mutations in the gene encoding this protein cause epidermolytic palmoplantar keratoderma.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171403Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051617Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Langbein L, Heid HW, Moll I, Franke WW (December 1993). "Molecular characterization of the body site-specific human epidermal cytokeratin 9: cDNA cloning, amino acid sequence, and tissue specificity of gene expression". Differentiation. 55 (1): 57–71. doi:10.1111/j.1432-0436.1993.tb00033.x. PMID 7507869.
  6. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  7. ^ Reis A, Hennies HC, Langbein L, Digweed M, Mischke D, Drechsler M, Schröck E, Royer-Pokora B, Franke WW, Sperling K (February 1994). "Keratin 9 gene mutations in epidermolytic palmoplantar keratoderma (EPPK)". Nat. Genet. 6 (2): 174–9. doi:10.1038/ng0294-174. PMID 7512862. S2CID 31277241.

Further reading

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